How to Revise IGCSE Biology Topic 3: Movement In and Out of Cells
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Reviewer participation may vary by guide. Checked against Cambridge IGCSE Biology 0610 (2026–2028); last reviewed August 2026.
Key point
Nail the exact definitions of diffusion, osmosis, and active transport. Practise predicting osmosis outcomes in different solutions. Be able to compare all three in a table.
Topic 3 is one of the most commonly tested topics in IGCSE Biology. You must know precise definitions for diffusion, osmosis, and active transport, and be able to explain examples and predict outcomes of osmosis experiments.
Priority 1: Definitions
Learn the exact definitions: every word matters:
Diffusion: net movement of particles from a region of higher concentration to a region of lower concentration
Osmosis: net movement of water molecules from a region of higher water potential (dilute solution) to a region of lower water potential (concentrated solution) through a partially permeable membrane
Active transport: movement of ions or molecules from a region of lower concentration to higher concentration (against the concentration gradient), requiring energy from respiration
Priority 2: Osmosis experiments
Predict what happens to plant cells and animal cells in different solutions. In a dilute solution: plant cells become turgid (vacuole swells, pushes against cell wall); animal cells swell and may burst (lysis). In a concentrated solution: plant cells plasmolyse (vacuole shrinks, membrane pulls away from wall); animal cells crenate (shrink and wrinkle).
Priority 3: Comparing all three
Know how to compare diffusion, osmosis, and active transport in a table: what moves, direction, energy requirement, membrane needed, examples.
Frequently asked questions
What is the most common mistake?
Defining osmosis without mentioning a partially permeable membrane. This is a required part of the definition.
Put the guide into practice
Questions and practical resources
Use a fresh question to check whether the idea can be applied without prompts.