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IGCSEBiology

Active immunity

Exam-ready definition

Defence against a pathogen by the production of antibodies in the body, gained after an infection or by vaccination.

How this is marked

The paying point is that the body makes its own antibodies, which is why active immunity is long-lasting (memory cells remain). Contrast this with passive immunity, where antibodies are given from outside and are short-lived. Students drop marks by forgetting memory cells, or by saying vaccination gives 'antibodies' rather than triggering the body to make them. Common in Paper 4 immunity questions.

In an exam answer

Explaining why a vaccine gives lasting protection: 'Vaccination produces active immunity because the body makes its own antibodies and memory cells, which respond quickly if the pathogen enters again.'

Full topic guide: Diseases & immunity

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